Control of metabolic genes is expected to inhibit excessive obesity

University of Virginia and the Medical College of Wisconsin scientists have found that, involved in the regulation of the body's physiological rhythms of a gene may also control metabolism is an important factor। This discovery will help find inhibit weight gain in an effective manner.

According to the Science Daily website of the United States recently reported that scientists in the study shows, Night lack of protein (Nocturnin) gene -- the gene in mammalian organs and tissues of the circadian clock regulation - - The Effect of high fat diet intake in rats when no increase in body weight, liver would not hoarding fat। This new understanding may help people find inhibition and reduce obesity to adverse health effects.

The study report's main author, University of Virginia biology professor Carla Green said : "It has long been known, Clock and physiological functions and metabolic aspects are inextricably linked. The study shows that Clock Night protein is used to control metabolism important aspect of the system. Better understanding of protein function night final People may find a solution to the problem of obesity treatments. "Biological Clock is the body's internal clock, By controlling the energy, vigilance, growth, aging and emotional impact to regulate organs and activities, rest cycle. Research in the field related to aging, jetlag, sleep disorders, shift work and dieting, and so on. Green and his colleagues used in experiments is normal mice and damaged the night protein gene mutation rats. Lost night protein rats were divided into two groups, one group of normal intake of food, another group of intake Effect of high fat diet. Gene normal rats also a group intake Effect of high fat diet. The researchers found that genetic mutation of the two groups of rats weight and activity levels remained normal. Effect of high fat diet intake, especially a group for a long time only a small increase in weight. However, the normal intake Effect of high fat diet rats were "inflated like a balloon as" increase the weight variation of the mouse body weight more than two times. Researchers found the anatomy, as expected, normal rat liver accumulation of a lot of fat, Variation of the two groups of rats and liver lipid levels remained normal. Green and his colleagues wrote in a recent report published in the published in the "Journal of the National Academy of Science" magazine on.